A video interview with Carolyn Dean, MD, ND. 

A magnesium deficiency amplifies depression and stress. The feel good brain chemical known as serotonin is increased artificially by some meds is dependent on magnesium for its production and function.

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A person who is under stress without ample levels of magnesium can become depleted and deficient in this vital mineral which if not remedied, can linger, causing depression and further health issues.

Magnesium deficiency can be an underlying cause of anxiety and depression, as determined in several clinical trials as referenced in the following:

http://www.ncbi.nlm.nih.gov/pubmed/16542786?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

http://george-eby-research.com/html/depression-anxiety.html

Symptoms of chronic magnesium deficiency include paranoia, anxious behavior, depression, hyper-emotionality, apprehension, confusion, anger, nervousness, insomnia, and nervous fits to name a few.